CB1 – TerpeneTargets

Silexan

Silexan targets two types of voltage gated calcium channels that human and rodent studies have shown to decrease anxiety. Lyrica also targets these channels. This post attempts to explain a very technical study to well motivated lay readers.

p-cymene

p-Cymene is anti-bacterial. Is it also inhibit mammalian mitochondria? Yes, it uncouples respiration of isolated micochondria.

Terpinene

This post examines some biological actions and possible targets of four of the major terpenes in tea tree oil.

CB1 and cholesterol

Can terpenes interact directly with CB1? Terpenes share some features with cholesterol, a modulator of CB1. This post examines the interaction of cholesterol with CB1.