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terpenes, their biological targets and cannabinoid entourage

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Category Archives: CB1

Silexan

Silexan targets two types of voltage gated calcium channels that human and rodent studies have shown to decrease anxiety. Lyrica also targets these channels. This post attempts to explain a very technical study to well motivated lay readers.

Posted byBLMay 21, 2022June 10, 2022Posted inCB1, VGCCTags:anxiety, lavender, linalool, SilexanLeave a comment on Silexan

p-cymene

p-Cymene is anti-bacterial. Is it also inhibit mammalian mitochondria? Yes, it uncouples respiration of isolated micochondria.

Posted byBLFebruary 27, 2022July 7, 2022Posted inCB1, mitochondria, trpTags:endocannabinoid, p-cymene, thymolLeave a comment on p-cymene

Terpinene

This post examines some biological actions and possible targets of four of the major terpenes in tea tree oil.

Posted byBLDecember 21, 2021December 25, 2021Posted inCB1, CB2, GABAA, trpTags:tea tree oil, terpinen-4-ol, terpineol, terpinonene1 Comment on Terpinene

CB1 and cholesterol

Can terpenes interact directly with CB1? Terpenes share some features with cholesterol, a modulator of CB1. This post examines the interaction of cholesterol with CB1.

Posted byBLDecember 1, 2021December 12, 2021Posted inCB1, membraneLeave a comment on CB1 and cholesterol
  • Home
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  • endocannabinoids
  • phytocannabinoids
  • Trp Channels
  • G Protein Coupled Receptors
  • CytP450s
  • GABAA receptor
  • terpenes
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