VGCC – TerpeneTargets

Eucalyptol

This post makes the case that eucalyptol, aka 1,8-cineole, is an activator of TRPM8 and an inhibitor of the L-type voltage gated calcium channel found in smooth muscle.

Silexan targets two types of voltage gated calcium channels that human and rodent studies have shown to decrease anxiety. Lyrica also targets these channels. This post attempts to explain a very technical study to well motivated lay readers.