How can something like capsaicin of chili pepper fame/infame hurt like bloody hell and then have analgesic properties? We have covered the TRP family of Ca2+ channels on a page on this site. Nature has given us a negative feedback mechanism byway of a small Ca2+ modulated protein that we call calmodulin, of CaM forContinue reading “Turning TRPV1 off”
Tag Archives: trpv1
Myrcene, Terpenes, and TrpV1
This study came out of the laboratory of experimental medicine in Honolulu Hawaii. As a general background it might be worth while to review Ca2+-calmodulin inhibition of this Ca2+ channel and and Trp family overview. This group selected myrcene and and a mixture of strain inspired terpenes. The latter was identified as dominant terpenes inContinue reading “Myrcene, Terpenes, and TrpV1”